The BCL3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BCL3. This antibody recognizes Human, and Mouse antigen. The BCL3 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B